Bota Bio 恩和生物
Bota Biosciences is a global leader in Physical AI-driven biomanufacturing, dedicated to making biotechnology a reliable and scalable engine of productivity. By integrating end-to-end capabilities in AI, synthetic biology, and industrialization, Bota pioneers a new paradigm in biomanufacturing research and production. Our world-leading Physical-AI driven biofoundry platform spans strain …
Profile
Bota Biosciences (Bota) is an active, privately held synthetic biology company founded in 2019 that specializes in AI-driven biomanufacturing for food, nutrition, and personal care ingredients. Headquartered in Lafayette, California, with significant operations in Hangzhou, China, the company utilizes its proprietary Physical AI-driven biofoundry platform to engineer enzymes, proteins, and peptides.
Key products include bio-preservatives (HeliaGenesis brand) and personal care ingredients (Yucca Elements brand). Bota operates a 130,000 square meter fermentation plant with over 600 tons of annual capacity. The company has raised approximately $237 million in total funding from investors including Sequoia Capital China, Matrix Partners China, and BASF Venture Capital.
Recent 2025-2026 developments include the launch of the SAION AI platform, a strategic partnership with Proya Cosmetics, and the 2026 market introduction of bio-identical Collagen III with BASF and Re2 Coffea Arabica Peptide with Syensqo.
Sources#
- Home - English - Bota | 恩和科技 — 2024-07-31
- About Bota - Bota | 恩和科技 — 2024-09-12
- Bota Biofoundry - Bota | 恩和科技 — 2024-08-09
- Bota Bio — Whiteford Research Biobase
- Bota Biosciences and Syensqo Expand Re2 Coffea Arabica Peptide to Global Personal Care Market - Bota | 恩和科技 — 2026-03-24
- News - Bota | 恩和科技 — 2024-09-29
- Bota Biosciences — 2026-06-26
- Proya Partners with Bota in Its First Strategic Move into Synthetic Biology - Bota | 恩和科技 — 2025-05-21
- Industry
- Cosmetics, Bioprocess equipment, Industrial chemistry, Post-harvest & processing, Veterinary
- Topics
- Synthetic biology platforms & biomanufacturing, Enzymes & biocatalysis
- Role
- Producer — “…sites & capacity** - First manufacturing site established — Nisin ( ) - Second factory campus of the Bota bio-…”
Bio-solutions it supplies 2
What they offer
Products: Nisin; Yucca Elements; HeliaGenesis; Prorylia®; Fibronectin; Reuse and Recycle Re²; SAION AI; Bota Smart Colony PCR Pipeline; Anne; Rapid Iterative Enzyme Engineering
Certifications: ISO 9001:2015
- Applications
- nutrition · food · personal care · animal health · Dairy · Drug intermediates · Food · Nutrition · Agriculture
- Certifications (website)
- ISO 9001:2015
- Production sites
- First manufacturing site established — Nisin · Second factory campus of the Bota bio-manufacturing site · biomanufacturing technologies · Hangzhou, China · Lafayette, CA, United States · 130,000 m² fermentation production plant — over 600 tons; bio-preservatives and ingredients
- Products (website)
- Nisin — First biopreservative product launched. · Yucca Elements — Personal care brand. · HeliaGenesis — Bio-preservative and food nutrition brand released. · Prorylia® · Fibronectin · Reuse and Recycle Re² · SAION AI — the first Physical AI platform for biomanufacturing · Bota Smart Colony PCR Pipeline — A variety of algorithms and machine learning models to simplify the PCR process. · Anne — The Smart Research Assistant for Synthetic Biology. · Rapid Iterative Enzyme Engineering — A biocatalysis solution that employs natural catalysts to facilitate chemical reactions, enhancing yields and reducing environmental pollution. · HeliaGenesis — HeliaGenesis is committed to advancing biotech solutions for the food and nutrition industries, specializing in producing high-quality bio-preservatives, nutritional supplements, and clean label products. · YuccaElements — YuccaElements is pioneering the research and development of natural, pure, and high-efficiency synthetic biological materials for global personal care ingredients and product formulations.
- R&D facilities
- LEAP R&D Center
Read from the company's own website: about · products · production · rnd · leadership · contact · sustainability · topic
Subsidiaries: HeliaGenesis · Yucca Elements
News & status 6
- 2026-03 Latest status: The company changed its Chinese short name from "恩和生物" to "恩和科技" on March 9, 2026. ↗ ↗ ↗
- 2026-03-09 恩和科技：以 Physical AI 定义生物制造新范式 - Bota | 恩和科技Bota Bio (恩和生物) is rebranding to 恩和科技 and positions itself as a global leader in Physical AI-driven biomanufacturing, aiming to transform biotech R&D into scalable, intelligent industrial production through end-to-end DBTL–embedded systems that convert biology …
- 2026-06-30 恩和科技+巴斯夫，推出AI驱动人源重组III型胶原蛋白_生物基和生物制造产业服务平台Bota (恩和科技) 与 BASF 共同推出 SkinNexus™ Collag3n，一种酵母发酵、与人体III型胶原蛋白序列100%一致的纯素重组胶原蛋白片段，已在全球市场上市并用于个人护理；产品通过“AI驱动的生物铸造”实现从发现到放大生产的闭环开发，且在3D真皮模型和临床前研究中显示提升多种胶原类型并改善皮肤松弛与皱纹。
- 2026-06-22 从代码到产线：恩和发布BPL协议语言，定义生物制造的“工业级编译器” - Bota | 恩和科技Bota | 恩和科技 (Bota Bio) 宣布发布 BPL（Biology Protocol Language）及其自动化生成管线 BPL-COGEN，构建可编译、可验证的生物实验协议语言与闭环生成-验证-修复机制，实现从自然语言到可执行、可跨平台迁移的工业级编译器，推动生物制造向可验证、高效的工业化方向发展。
- 2026-04-02 Synbio China 回顾 | 恩和科技联合发起“AI+生物制造”专场：Physical AI如何真正落地？ - Bota | 恩和科技Bota Bio (恩和科技) is presented as a global leader in Physical AI-powered biomanufacturing, driving end-to-end, scalable biomanufacturing from strain engineering to production and partnering with clients to enable greener, more efficient, industrial-scale bio …
- 2026-03-26 恩和受邀出席BIOKET全球生物经济高峰论坛， 与欧莱雅、赢创、Amyris 共探生物制造创新标准-乐商网Bota Bio (恩和科技) CTO 戴翊书在 BIOKET 全球生物经济高峰论坛上作主旨演讲，介绍了 SAION AI 这样的“物理AI”平台，强调将数字设计直接转化为自动化执行以解决生物制造的产业化挑战。公司还表示已与巴斯夫、世索科等伙伴合作，围绕从分子发现到工业交付形成闭环，推动生物制造向产业化落地与绿色转型。
- 2026-06-01 喜报！全球首家！瑞旭CIRS助力恩和科技ZeaVida®精准发酵玉米黄质获批FDA GRAS认证 | 新闻 | 食规查Bota Bio (恩和科技) is presented as a global leader in physically AI-driven biomanufacturing, integrating AI, synthetic biology, and industrial-scale processes to enable scalable, sustainable production, including ZeaVida® with FDA GRAS clearance as a milestone …
Network: owners, partners, peers
Ownership & investors 11
| parent | Bota Biosciences |
| investor | Matrix Partners China |
| investor | Sherpa Healthcare Partners |
| investor | Baidu Ventures |
| investor | BASF Venture Capital |
| investor | Sequoia Capital China |
| investor | Source Code Capital |
| investor | Meituan |
| investor | CMB International Capital |
| subsidiary | HeliaGenesis |
| subsidiary | Yucca Elements |
Partners & deals 1
| collaboration | Capital …re Capital.
Recent 2025-2026 developments include the launch of the SAION AI platform, a strategic partnership with Proya Cosmetics, and the 2026 market introduction of bio-identical Collagen III …… |
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