# Broad Institute

Genetic Perturbation Platform (GPP) — reference genome-wide libraries.

Source: https://en.bioecon.ru/companies/broad-institute/
Updated: 2026-06-24

- Country: United States

## Verifiable facts

| Fact | Value | Source |
| --- | --- | --- |
| Affiliation | Broad Institute of MIT and Harvard | https://www.broadinstitute.org/genetic-perturbation-platform |
| Research focus | Development and application of functional genomic tools, including CRISPR technologies for large-scale genetic screens, gene expression, and RNA interference. | https://portals.broadinstitute.org/gpp/public/, https://www.broadinstitute.org/genetic-perturbation-platform, https://www.broadinstitute.org/technology-platforms |
| Principal staff | David Root (Senior Director), John Doench (Senior Director R&D) | https://www.broadinstitute.org/bios/david-root, https://www.broadinstitute.org/scientific-community/science/platforms/gpp/team |
| Publications | Over 9,716 total publications to date (for the Broad Institute as a whole) | https://www.broadinstitute.org/files/news/media-kit/BroadFactSheet.pdf |
| Partnership | Functional Genomics Consortium (including AbbVie, Bristol Myers Squibb, Janssen, Merck, and Vir Biotechnology) [medium confidence] | https://www.nature.com/articles/s41467-026-76648-4 |
| Partnership | Center for Basic Metabolic Research (CBMR) at the University of Copenhagen [medium confidence] | https://cbmr.ku.dk/research-facilities/gpp/ |

Independent sources: cbmr.ku.dk, nature.com

## Technologies

- [Base editing](https://en.bioecon.ru/technology/base-editing/)
- [CRISPR screening as a service](https://en.bioecon.ru/technology/crispr-screening-as-a-service/)
- [Long-read sequencing services](https://en.bioecon.ru/technology/long-read-sequencing-services/)
- [Prime editing](https://en.bioecon.ru/technology/prime-editing/)