# Buck Institute for Research on Aging

the Marin County, CA-based Buck Institute for Research on Aging published a new blood-based epigenetic clock in June 2025 focused on "intrinsic capacity" rather than raw age, and is running its BIG Study biobank to collect blood at scale for aging research;…

Source: https://en.bioecon.ru/companies/buck-institute-research-on-aging/
Updated: 2026-08-15

- Country: United States

## Verifiable facts

| Fact | Value | Source |
| --- | --- | --- |
| Research focus | intrinsic capacity (IC) and biological age clock using DNA methylation (2025-06-04) | https://doi.org/10.1038/s43587-025-00883-5, https://www.buckinstitute.org/news/a-new-blood-based-epigenetic-clock-for-aging-focuses-on-intrinsic-capacity/, https://www.buckinstitute.org/wp-content/uploads/2025/10/impact-report-2025-v2.5-web.pdf, https://www.marinbio.com/measuring-healthy-aging-with-the-intrinsic-capacity-ic-clock-a-functional-aging-breakthrough/ |
| Facility | Bill and Mary Poland Clinical Research Unit (CRU) | https://www.buckinstitute.org/wp-content/uploads/2025/10/impact-report-2025-v2.5-web.pdf |
| Grant | up to $52 million award from ARPA-H for PATH research initiative | https://www.buckinstitute.org/wp-content/uploads/2025/10/impact-report-2025-v2.5-web.pdf |
| Publications | 110+ scientific papers published each year | https://www.buckinstitute.org/wp-content/uploads/2025/10/impact-report-2025-v2.5-web.pdf |
| Principal staff | Eric Verdin (President and CEO), Malene Hansen (Chief Scientific Officer), Lee Hood (Chief Innovation Officer) | https://www.buckinstitute.org/, https://www.buckinstitute.org/wp-content/uploads/2025/10/impact-report-2025-v2.5-web.pdf |
| Affiliation | IHU HealthAge (France), Phenome Health | https://www.buckinstitute.org/news/a-new-blood-based-epigenetic-clock-for-aging-focuses-on-intrinsic-capacity/, https://www.buckinstitute.org/wp-content/uploads/2025/10/impact-report-2025-v2.5-web.pdf |

Independent sources: doi.org, marinbio.com

## Technologies

- [Epigenetic clocks & biological-age diagnostics](https://en.bioecon.ru/technology/epigenetic-clocks-biological-age-diagnostics/)