# CytoNiche

a Tsinghua Medical School spin-off whose microcarriers carried the first stem-cell drug approved in China (2025) after partner 铂生卓越 switched its phase III MSC process from 2D to 3D in 2022; closed a B+ round of several hundred million RMB (2025) from Beijing municipal funds, ICBC and CICC.

Source: https://en.bioecon.ru/companies/cytoniche/
Updated: 2026-07-26

- Country: China

## Verifiable facts

| Fact | Value | Source |
| --- | --- | --- |
| Funding | raised total funding of approximately $94.9M across multiple rounds, including a series B+ round of several hundred million RMB and a Series B round of approximately $47.5M | https://biospectrumasia.com/opinion/98/22667/enhancing-cell-and-gene-therapy-scalability-in-asia-using-3d-manufacturing-platforms-with-microcarrier-technology.html, https://www.vcbeathealth.com/article/1742 |
| Capacity | annual output of 300 kg for microcarriers and 300,000 bottles for culture medium additives | https://www.vcbeathealth.com/article/1742 |
| Certification | GMP-grade microcarriers registered under Type IV & Type II DMF (U.S. FDA) | https://en.cytoniche.com/story.html |
| Regulatory approval | 3D FloTrix platform technology supported the approval of China's first stem cell drug (Amimestrocel Injection) on January 2, 2025 | https://en.cytoniche.com/News_detail/24.html, https://en.cytoniche.com/story.html, https://synapse.patsnap.com/organization/4ff6ac48b37cfaa52ed2d84d5f550c52, https://www.vcbeathealth.com/article/1742 |
| Production site | GMP production platform of 6,000 square meters, including a 4,000 square meter Tianjin cGMP production center and a research and development platform of nearly 7,000 square meters | https://biospectrumasia.com/opinion/98/22667/enhancing-cell-and-gene-therapy-scalability-in-asia-using-3d-manufacturing-platforms-with-microcarrier-technology.html, https://www.vcbeathealth.com/article/1742 |
| Headcount | reported between 4 and 7 employees as of 2026 [medium confidence] | https://www.caplight.com/company/cytoniche |

Independent sources: biospectrumasia.com, caplight.com, synapse.patsnap.com, vcbeathealth.com

## Technologies

- [Microcarriers for adherent cell cultures](https://en.bioecon.ru/technology/microcarriers-adherent-cell-culture/)