# HTL Biotechnology

HTL Biotechnology in Brittany (a more than 64,000 m² site) is a global leader in pharmaceutical-grade biopolymers, running fermentation through extraction and purification on a solvent-free route and inaugurating a new sterile hyaluronic-acid production line on 6 June 2025.

Source: https://en.bioecon.ru/companies/htl-biotechnology/
Updated: 2026-06-28

- Country: France

## Verifiable facts

| Fact | Value | Source |
| --- | --- | --- |
| Funding | Majority stake acquired by Montagu (2022) | https://htlbiotech.com/wp-content/uploads/2024/01/20220208-htl-announces-montagu-as-new-investor.pdf |
| Capacity | Includes four independent production units for hyaluronic acid and polynucleotides; capacity increased by factor of 2.3 for hyaluronic acid with HTL4 unit | https://htlbiotech.com/about-us/our-company/our-latest-investments/, https://htlbiotech.com/about-us/our-company/our-production-department/, https://htlbiotech.com/our-industrial-platform/ |
| Certification | ISO 13485, ISO 14001, and Halal certification | https://htlbiotech.com/about-us/our-company/our-production-department/, https://htlbiotech.com/blog/excellence-in-quality-the-foundation-of-htl-biotechnologys-pharma-grade-biopolymers/, https://htlbiotech.com/wp-content/uploads/2024/12/htl-rapport-rse-2023-gb.pdf |
| Regulatory approval | Site periodically inspected by FDA and ANSM; complies with cGMP Part II for API manufacture | https://htlbiotech.com/about-us/our-company/our-production-department/ |
| Production site | Historic site in Javené, Brittany, France (over 64,000 m²); production unit in the United States; production unit under construction in Boston | https://htlbiotech.com/about-us/our-company/our-production-department/, https://htlbiotech.com/our-industrial-platform/, https://htlbiotech.com/wp-content/uploads/2024/12/htl-rapport-rse-2023-gb.pdf |
| Headcount | Approximately 179 to 300 employees worldwide [medium confidence] | https://htlbiotech.com/wp-content/uploads/2024/12/htl-rapport-rse-2023-gb.pdf |
| Revenue | Reported as 100M turnover (2023 report), $27.8M (LinkedIn/CB Insights), or $44.2M (Growjo) [medium confidence] | https://htlbiotech.com/wp-content/uploads/2024/12/htl-rapport-rse-2023-gb.pdf, https://www.clodura.ai/directory/company/htl-biotechnology |

Independent sources: clodura.ai

## Technologies

- [Biosynthetic hyaluronic acid](https://en.bioecon.ru/technology/biosynthetic-hyaluronic-acid/)
- [Recombinant collagen & gelatin](https://en.bioecon.ru/technology/recombinant-collagen-gelatin/)