Companies
Imperial College London
developed the iKnife (Intelligent Knife), which uses rapid evaporative ionization mass spectrometry (REIMS) to analyze the aerosol generated by electrosurgical cutting in real time and identify tissue type from its lipidomic signature, commercialized in partnership with Waters Corporation's mass-spectrometry platforms.
- Country
- United Kingdom
iKnife (REIMS)
Coverage
| CN | EU | US | |
|---|---|---|---|
| diagnostics-medtech | ✓ | ✓ | ✓ |
Regulatorsfdaemanmpa
Verifiable facts
| Fact | Value | Source |
|---|---|---|
| Affiliation | Section of Biomolecular Medicine, CRUK Convergence Science Centre, Cancer Technology Network, Clinical Phenotyping Centre, Computational Medicine, Institute for Molecular Science and Engineering, Microbiome Network, National Phenome Centre, UK Dementia Research Institute at Imperial, Wound Healing and Regeneration Network, Zoltan Takats Group | profiles.imperial.ac.uk |
| Research focus | Mass spectrometry, specifically ambient mass spectrometry and rapid evaporative ionization mass spectrometry (REIMS) for real-time intraoperative tissue diagnostics | profiles.imperial.ac.uk · imperial.ac.uk · mdpi.com · queensu.ca |
| Facility | National Phenome Centre, Clinical Phenotyping Centre, Imperial Experimental Cancer Medicine Centre, Imperial College NHS Foundation Trust (Charing Cross Hospital), Sir Alexander Fleming Building | clinicaltrials.gov · imperialbrc.nihr.ac.uk · phenomecentre.org · profiles.imperial.ac.uk · ecmcnetwork.org.uk |
| Grant | European Research Council (Starting Grant and Proof-of-Concept Grant), National Institute for Health and Care Research (NIHR), Hungarian National Office for Research and Technology, Medical Research Council’s Imperial Confidence in Concept Scheme, Waters Corporation research funding | erc.europa.eu · pmc.ncbi.nlm.nih.gov · profiles.imperial.ac.uk · spiral.imperial.ac.uk · imperial.ac.uk |
| Publications | 78 peer reviewed publications as of early 2012 | profiles.imperial.ac.uk |
| Principal staff | Zoltan Takats (Professor of Analytical Chemistry), Ara Darzi (Professor of Surgery), Jeremy Nicholson (Head of Department of Surgery and Cancer) | imperialbrc.nihr.ac.uk · profiles.imperial.ac.uk · imperial.ac.uk |
| Headcount | Dedicated research staff (number not specified) medium confidence | ecmcnetwork.org.uk |
Independent sources: clinicaltrials.gov · ecmcnetwork.org.uk · erc.europa.eu · imperialbrc.nihr.ac.uk · mdpi.com · phenomecentre.org · pmc.ncbi.nlm.nih.gov · profiles.imperial.ac.uk · queensu.ca · spiral.imperial.ac.uk
Technologies
| Name | Cluster | Risk | |
|---|---|---|---|
| Intraoperative molecular diagnostics | diagnostics-medtech | Medium | → |
Compiled by BIOECON from primary sources.
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