# Peking University

researchers Chen Peng (College of Chemistry and Molecular Engineering) and Yi Chengqi (School of Life Sciences) published a June 2025 codon-expansion strategy using post-transcriptionally modified RNA codons — distinct from all 64 standard codons — to incorporate ncAAs into mammalian systems without disturbing the natu…

Source: https://en.bioecon.ru/companies/peking-university/
Updated: 2026-08-15

- Country: China

## Verifiable facts

| Fact | Value | Source |
| --- | --- | --- |
| Affiliation | Peking University | https://newsen.pku.edu.cn/news_events/news/research/15016.html, https://www.bio.pku.edu.cn/en/index/detail-2187.html, https://www.chem.pku.edu.cn/chenpeng/ |
| Research focus | RNA codon expansion, genetic code expansion, non-canonical amino acid incorporation, epitranscriptomics, and genome editing | https://newsen.pku.edu.cn/news_events/news/research/15016.html, https://www.bio.pku.edu.cn/en/index/index/by_speciality_detail/cid/70/id/7.html |
| Facility | Synthetic and Functional Biomolecules Center (SFBC), Peking-Tsinghua Joint Center for Life Science, and Biomedical Pioneering Innovation Center (BIOPIC) | https://www.bio.pku.edu.cn/en/index/index/by_speciality_detail/cid/70/id/7.html, https://www.chem.pku.edu.cn/chenpeng/, https://www.rcsb.org/structure/5YTG |
| Grant | National Basic Research Foundation of China (Grant 2014CB964900) and National Natural Science Foundation of China (Grants 31270838 and 21522201) [medium confidence] | https://www.rcsb.org/structure/5YTG |
| Publications | RNA codon expansion via programmable pseudouridine editing and decoding (Nature, 2025) | https://newsen.pku.edu.cn/news_events/news/research/15016.html, https://pubmed.ncbi.nlm.nih.gov/40562925/, https://www.chem.pku.edu.cn/chenpeng/ |
| Principal staff | Chen Peng and Yi Chengqi | https://www.bio.pku.edu.cn/en/index/index/by_speciality_detail/cid/70/id/7.html, https://www.chem.pku.edu.cn/en/People/AcademicStaff/6d7745187c2849749be412527c6d9c01.htm |

Independent sources: bio.pku.edu.cn, chem.pku.edu.cn, newsen.pku.edu.cn, pubmed.ncbi.nlm.nih.gov, rcsb.org

## Technologies

- [Xenobiology & expanded genetic alphabet (XNA)](https://en.bioecon.ru/technology/xenobiology-expanded-genetic-alphabet/)