Companies
SIMM (CAS)
operates a cryo-electron-microscopy structural biology center (established 2018) studying G-protein-coupled receptors (GPCRs) — the receptor class serotonin 5-HT2A belongs to — providing atomic-resolution structural data that supports AI-driven design of biased, non-hallucinogenic agonists.
- Country
- China
structural-biology
cn
Coverage
| CN | EU | US | |
|---|---|---|---|
| therapeutics-platforms | ✓ | ✓ | ✓ |
Regulatorsfdaemanmpa
Verifiable facts
| Fact | Value | Source |
|---|---|---|
| Affiliation | Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences (CAS) | simm.cas.cn |
| Research focus | Structure, function, and signaling of G-protein-coupled receptors (GPCRs), including serotonin receptors, ion channels, and nuclear receptors; drug discovery and design | simm.cas.cn |
| Facility | Center of Cryo-Electron Microscopy (established 2018); CAS Key Laboratory of Receptor Research | simm.cas.cn · pmc.ncbi.nlm.nih.gov |
| Grant | National Key R&D Programs of China (2018YFA0507002), Shanghai Municipal Science and Technology Major Project (2019SHZDZX02), CAS Strategic Priority Research Program (XDB37030103), National Natural Science Foundation of China (31770796, 81922071), National Science and Technology Major Project (2018ZX09711002-002-002) | pmc.ncbi.nlm.nih.gov · research.vu.nl |
| Headcount | 74 fixed members in the CAS Key Laboratory of Receptor Research medium confidence | simm.cas.cn |
| Principal staff | Yu Xui (Director, Center of Cryo-Electron Microscopy); Xu H. Eric (Director, CAS Key Laboratory of Receptor Research); Zhao Qiang (Deputy Director of SIMM) | english.simm.cas.cn · simm.cas.cn |
Independent sources: pmc.ncbi.nlm.nih.gov · research.vu.nl
Technologies
| Name | Cluster | Risk | |
|---|---|---|---|
| Psychedelic medicine & neuropsychiatric biologics | therapeutics-platforms | High | → |
Compiled by BIOECON from primary sources.
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