https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/Recent content in Bioinformatics & omics on BioeconHugoen-UShttps://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/bioinformatics-multi-omics/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/bioinformatics-multi-omics/Why stacking omics layers rarely multiplies the signal, and usually multiplies the noise.https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/biocomputing-dna-computing/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/biocomputing-dna-computing/DNA is an extraordinary archive and a poor computer, and the reasons are physical.https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/biological-ai-bioinformation-services/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/biological-ai-bioinformation-services/Why a model trained on sequence alone learns structure, and where that inference stops.https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/genomics-dna-design/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/genomics-dna-design/What can be ordered as DNA is decided by chemistry, and what it does is decided by more than codons.https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/long-read-sequencing-services/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/long-read-sequencing-services/Two very different physical measurements, one shared advantage: the read is longer than the problem.https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/metabolomics-service/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/metabolomics-service/The only omics layer whose molecules share no common backbone — which is why no single method sees it.https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/proteomics-mass-spec-cro/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/proteomics-mass-spec-cro/Proteins cannot be amplified, and that single fact makes proteomics harder than genomics.https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/single-cell-omics/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/single-cell-omics/Every artefact of the method — dropout, doublets, ambient RNA, stress response — is a consequence of how the cell got into the tube.https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/spatial-epigenomics/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/spatial-epigenomics/Reading chromatin state in place, where the measurement is nearly binary and the per-cell data are sparser than anything in transcriptomics.https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/spatial-transcriptomics-spatial-multi-omics/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/spatial-transcriptomics-spatial-multi-omics/Two families with opposite compromises: capture that is unbiased but mixes cells, imaging that is precise but sees only a panel.https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/structural-biology-cryo-em-cro/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/structural-biology-cryo-em-cro/The microscope is rarely the limit; the thin film of ice and the molecule’s own flexibility are.https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/toxics-screening-toxicomics-service/Mon, 01 Jan 0001 00:00:00 +0000https://en.bioecon.ru/docs/synbio-enabling/bioinformatics-omics/toxics-screening-toxicomics-service/Using a molecular response as a stand-in for harm, and the concordance problem that decides whether it works.