Industries
Research tools & R&D services
What changes this industry: bio-solutions with evidence, technologies, suppliers and open money.
Overview of the industry
The instruments, services and platforms that biological research and biotech development run on: genome editing and CRISPR screening, DNA synthesis and gene foundries, long-read and nanopore sequencing, proteomics and metabolomics services, bioinformatics for multi-omics, protein design, and cell-free systems. Biobanks, reference materials and certified strains, and biosafety and DNA-synthesis screening are listed here too.
What it replaces 0
No graded substitution linked yet.
Technologies 34
| Biobanks of human & population samples Physical infrastructure for collecting, processing, cryopreserving and distributing human biospecimens at population or clinical-trial scale — the biospecimen … | Diagnostics & medtech |
| Bioinformatics & multi-omics Sequencing, single-cell and spatial omics, and biological AI that turn raw reads into decisions — a stack from sample to interpreted multi-omics. | Bioinformatics & omics |
| Bioluminescence & marine fluorescent proteins Engineered luciferases and fluorescent proteins derived from jellyfish, deep-sea shrimp and other marine organisms, redesigned via directed evolution and … | Marine biotech |
| Biosafety & lab biosecurity Physical-containment infrastructure — biological safety cabinets, HEPA filtration, autoclave sterilization and BSL-1 to BSL-4 containment — that protects … | Genome engineering |
| CAD software for synthetic biology Computer-aided design software that lets a synthetic biologist draft a genetic construct, simulate its behavior and generate an assembly protocol before a … | Foundries & design |
| Cell-free systems & cell-free bioproduction Cell-free protein synthesis (CFPS) bypasses the living cell: ribosomes and translation factors in a reaction tube deliver the target protein in hours, not … | Foundries & design |
| CRISPR screening as a service Contract functional-genetic CRISPR screening (pooled sgRNA libraries, lentiviral delivery, NGS) — identifies cancer-resistance genes and drug targets in weeks. | Genome engineering |
| De novo protein design Proteins specified on a computer and realized in a lab — backbone geometry, binding interfaces and self-assembly designed from physical principles rather than … | Foundries & design |
| DNA nanotechnology & DNA origami Folding single-stranded DNA into precision-programmed 3D nanostructures — drug-delivery nanorobots, vaccine scaffolds and metrology nanorulers. | Foundries & design |
| DNA synthesis & gene foundry The commercial gene-synthesis service and biofoundry layer of synthetic biology — turning digital DNA designs into delivered genes, clones and strain builds … | Foundries & design |
| DNA synthesis biosecurity screening Screening every DNA and RNA synthesis order against a curated database of dangerous pathogen and toxin sequences before it is manufactured — commercial … | Genome engineering |
| Epigenome editing Turning genes on or off by rewriting DNA methylation and histone marks with dCas9 fusion proteins or zinc fingers — no DNA sequence change, but an effect that … | Genome engineering |
| Generative protein design Creating completely novel, non-natural protein structures and sequences from scratch using diffusion networks and large language models for therapeutics and … | Foundries & design |
| Genetic toggle-switch circuits Bistable gene circuits that let a cell hold a decision — two repressors wired against each other, from the Gardner–Collins toggle to industrial strains whose … | Foundries & design |
| Genome editing Programmable genome editors — CRISPR-Cas9, base editors and prime editors — delivered ex vivo or in vivo via lipid nanoparticles to treat genetic disease, from … | Genome engineering |
| Genomics & DNA design Writing genomes rather than just reading them — DNA synthesis at scale, de novo synthetic chromosomes and DNA-based digital data storage, complementing the … | Bioinformatics & omics |
| iGEM infrastructure, BioBricks and standard genetic parts The shared substrate synthetic biology runs on — a registry of standard parts and the student competition that populates it, nonprofit plasmid repositories, … | Foundries & design |
| Intelligent genetic switches (kill switches) Synthetic gene circuits that force engineered organisms to depend on external chemical signals for survival, self-destructing or losing viability once released … | Genome engineering |
| Long-read sequencing services Third-generation (long-read) sequencing as a service — PacBio HiFi and Oxford Nanopore platforms resolving repeats, structural variants and direct epigenetic … | Bioinformatics & omics |
| Metabolic engineering Rational design and optimization of microbial metabolic pathways to produce high-value chemicals, advanced materials, and alternative proteins at industrial … | Foundries & design |
| Metabolomics (service) Contract research platforms that profile the small-molecule metabolome of blood, tissue or bioreactor broth via LC-MS/GC-MS, turning raw chromatography data … | Bioinformatics & omics |
| Minimal genomes & synthetic cells The frontier of building life de novo — stripping genomes down to a minimal viable chassis (top-down) and assembling artificial cells from non-living parts … | Genome engineering |
| Nanopore direct RNA sequencing Reading native RNA molecules strand by strand through a protein nanopore — no reverse transcription, no amplification bias, base modifications visible in the … | Bioinformatics & omics |
| Proteomics (mass-spec CRO) Mass-spectrometry proteomics as a contract research service — deep DIA proteome profiling, targeted MRM/PRM and affinity proteomics for biomarker discovery and … | Bioinformatics & omics |
| Reference materials & certified reference strains Authenticated microbial type strains and WHO biological reference materials — the calibrated living standards underpinning pharmaceutical QC, diagnostics, … | Monitoring & conservation |
| Robotic biobanking and sample storage Automated ultra-low-temperature and liquid-nitrogen storage systems that robotically retrieve, track and manage individual sample tubes or plates at scale — the … | Analytics & PAT |
| Single-cell omics Per-cell mapping of genomes, transcriptomes and proteomes as a contracted service — moving biology from bulk-average reads to cell-by-cell atlases for … | Bioinformatics & omics |
| Spatial epigenomics Mapping chromatin accessibility, DNA methylation and histone marks directly on a tissue section instead of a dissociated cell suspension, using in situ Tn5 … | Bioinformatics & omics |
| Spatial transcriptomics & spatial multi-omics Mapping gene expression — and increasingly proteins — directly onto intact tissue sections, so each transcript keeps its x/y address and the tumour … | Bioinformatics & omics |
| Strain engineering (synbio CRO) Contract organisations that engineer the microbe or enzyme itself — directed evolution, computational protein design and genome editing of production strains — … | Crop biotech |
| Structural biology (cryo-EM CRO) Cryo-electron microscopy as a contract research service — atomic 3D structures of membrane proteins and drug targets for structure-based drug design, displacing … | Bioinformatics & omics |
| Synthetic biology The engineering of biology — designing DNA, cells and genetic circuits on computers, building them in biofoundries and scaling them into chemicals, materials … | Genome engineering |
| Toxics screening (toxicomics, service) Contract safety assessment that takes a drug candidate from in-silico ADMET triage through in-vitro panels (hepatotoxicity, hERG, CYP induction) to GLP in-vivo … | Bioinformatics & omics |
| Xenobiology & expanded genetic alphabet (XNA) Orthogonal biological systems built on xeno-nucleic acids, unnatural base pairs and genomically recoded organisms that incorporate noncanonical amino acids into … | Genome engineering |