Prime editing
Search-and-replace genome editing: a Cas9 nickase fused to reverse transcriptase, paired with an extended pegRNA, writes all 12 base substitutions plus small insertions/deletions without a double-strand break.
How it works
This is a procurement category, not a named manufacturer's product. As a paid service, Bioecon finds suppliers for your task, agrees configuration and specification, and arranges supply; the price is on request. Bioecon may receive a fee from suppliers — this is disclosed and does not affect the portal's grades or lists.
Technology
Prime editing — Evidence, registration route, funding and suppliers are on the technology page.
Search-and-replace genome editing with a Cas9 nickase fused to a reverse transcriptase and an extended pegRNA — writing all 12 base substitutions and small indels without a double-strand break.
Links
- Import and registration route
- CHEM — Minpromtorg (registration) / Rospotrebnadzor (notification of …
- Capabilities
- Testing & analytics