# Recombinant human serum albumin (rHSA)

Upstream — fermentation & cell culture — Recombinant human serum albumin (rHSA) replaces plasma-derived HSA (pHSA) — constrained by donor blood supply and viral-contamination risk since the 1940s — with the first FDA/EMA/PMDA-approved rice-derived rHSA for injection. The global rHSA market was $166M.

Source: https://en.bioecon.ru/market/upstream/recombinant-human-serum-albumin/