technology

High-fidelity gene synthesis

Commercial DNA manufacture where the frontier is sequence difficulty rather than length — tandem and inverted repeats, GC extremes and homopolymers that defeat conventional synthesis.

Where it's used

iGEM infrastructure, BioBricks and standard genetic parts
The shared substrate synthetic biology runs on — a registry of standard parts and the student competition that populates it, nonprofit plasmid repositories, commercial gene synthesis reaching 7,000 base pairs on complex sequences, and automated biofoundries whose assemblies are now validated by long-read sequencing.
foundries-design 11 min