technology

Impingement-jet mixing

Continuous LNP formation by colliding two high-velocity jets (organic lipid stream and aqueous mRNA stream) inside a confined chamber, the dominant mixer geometry for commercial mRNA vaccine manufacturing.

Where it's used

mRNA / LNP manufacturing equipment
The mixers, skids and continuous-flow reactors that bring an mRNA payload and a four-lipid ethanol blend together in microseconds to self-assemble 80–120 nm lipid nanoparticles — the hardware layer behind every commercial mRNA vaccine and the in-vivo delivery system for the next generation of gene therapy.
fill-finish-packaging 8 min