technology

Lentiviral vectors

Retroviral vectors (HIV-1-derived) that integrate into the host genome of both dividing and non-dividing cells, the standard platform for ex-vivo modification of haematopoietic stem cells and CAR-T.

Where it's used

In-vivo gene therapy: AAV and lentiviral vectors
One-time, potentially curative genetic medicines delivered by engineered adeno-associated and lentiviral vectors — eight FDA-approved in-vivo products since 2017, from Luxturna to Beqvez, now a multi-billion-dollar clinical reality alongside honest commercial retrenchments.
therapeutics-platforms 7 min