technology

Pharmaceutical crystallization

Controlled solidification of an active pharmaceutical ingredient from solution to set polymorph, particle-size distribution and purity; the unit operation that turns a purified molecule into a processable, bioavailable solid.

Where it's used

Crystallization equipment for pharmaceutical APIs
The stirred, draft-tube-baffled, melt and continuous crystallizers — plus the inline FBRM/PVM probes that close the loop on them — that turn a purified API molecule into a defined polymorph with a target particle-size distribution, the unit operation on which bioavailability, purity and downstream filterability all depend.
downstream-purification 7 min